Yes you should be pulling timing for anything over 15psi. If the motor does encounter knock, the knock sensor will detect this and pull timing. With that said the ECU will protect your motor to an extent but always pull several degrees of timing to reduce knock which will hurt your power.

You could also run MS for spark control

98 Eclipse GS Turbo
Built motor - MS2 - Holset hy35 - Zoom Stg 4 Clutch - 57.5mm TB - ARP Headstuds - Turbonetics wastegate - 3" Turbo back - FMIC - Greddy RZ BOV - Walbro 255 - 650cc Injectors - Fidanza Flywheel - Cobra calipers w/ 13" Rotors - Oil Cooler - DevilsOwn meth injection

1981 Chevy Scottsdale
1987 Nissan 300zx - Chump Car
2001 BMW 325i