I think one thing that we need to keep in mind is that we should not be running much above 80% duty.
I believe part of the reason why we tend to detonate at higher boost is because we are running these massive 12:1 FMU's and small injects 234cc..

So lets look at it this way :
234cc @ 43psi = 272cc @ 50psi (our cars)
Now to make things more interesting lets throw in some boost,
with along with a 12:1 FMU !
Correct me if im wrong but 8psi should put us right around 100psi. +/- a few psi.. (2.325 ratio)
100psi 8psi boost = 544cc ...which is 184% duty cycle !!
Injector lockup galore !! --hehehe